Health Condition 1: E889- Metabolic disorder, unspecified Health Condition 2: F88- Other disorders of psychological development
Conditions
Interventions
Intervention1: nil: nil
Control Intervention1: nil: nil
Sponsors
Dr Rochelle Natasha Gomes
Eligibility
Inclusion criteria
Inclusion criteria: 1. Children aged 1 month to 1 year admitted in the Department of Paediatrics and presenting with GDD (global developmental delay with unclear etiology, progressive encephalopathy with seizures, hypotonia with or without poor feeding, failure to thrive, respiratory distress or vomiting). 2. Children with hypoglycaemic encephalopathy.
Exclusion criteria
Exclusion criteria: 1. Children lesser than 1 month of age or older than 1 year at presentation. 2. Children with identified causes of GDD such as perinatal asphyxia/ hypoxic ischaemic encephalopathy stage 2 or 3, TORCH infections, post-meningitis sequelae, chromosomal disorder, hypothyroidism etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To establish the role of initial metabolic workup, Tandem Mass Spectrometry (TMS) and Gas Chromatography- Mass Spectrometry (GC-MS) in infants presenting with global developmental delay. Timepoint: 2 years | — |
Secondary
| Measure | Time frame |
|---|---|
| To obtain the clinical profile of infants presenting with GDD requiring metabolic workup. Timepoint: 2 years | — |
Countries
India
Contacts
Public ContactDr Sandesh Kini B
Kasturba Medical College and Hospital
Outcome results
None listed