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Comparison of effect of High Flow Nasal Cannula with Continuous Positive Airway Pressure in reducing incidence of invasive mechanical ventilation in severe COVID 19 patients.

Comparison of efficacy of HighFlow Nasal Cannula with Continuous Positive Airway Pressure in prevention of Invasive mechanical ventilation in COVID 19 patients with Acute Respiratory Distress Syndrome in Critical Care Unit- A Randomized Control Study - COVID HFNC

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/04/032501
Enrollment
60
Registered
2021-04-01
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere Health Condition 2: J96- Respiratory failure, not elsewhereclassified

Interventions

Intervention1: High flow nasal cannula HFNC: High Flow Nasal Cannula (HFNC) therapy is an alternative method of oxygen supplementation in critical care unit with COVID 19 patients. HFNC has been recom

Sponsors

SRM Medical College and Research Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All COVID -19 positive patients ( by RT-PCR) with paO2/Fio2 (P/F) ââ?¬â?? 150 to 250, with good sensorium, stable hemodynamics and pH > 7.2 Absence of nasal pathology

Exclusion criteria

Exclusion criteria: Hemodynamically unstable patients Patients in shock/ severe acidosis Epistaxis, basal skull fracture

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of High Flow Nasal Cannula and Non Invasive Ventilation -Continuous Positive Airway Pressure in reducing need for invasive mechanical ventilation in patients with ARDS in COVID-19.Timepoint: 24 hours—

Secondary

MeasureTime frame
Ability of ROX index to identify COVID 19 patients on HFNC requiring invasive mechanical ventilation.Timepoint: 24 hours;Ability to alleviate dyspnoea as assessed by modified Borg scaleTimepoint: 24 hours;Patientââ?¬â?¢s compliance to therapy - comfort / noise level, ability to proneTimepoint: 24 hours—

Countries

India

Contacts

Public ContactGunasri K

SRM Medical College

dranand@outlook.com9865282288

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026