Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: control group (Group C): Group C: will receive Etomidate induction dose of 0.3 mg/kg etomidate, injected manually over 20 s.
Control Intervention1: priming group (Group P): Group P: wi
Sponsors
M S Ramaiah Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Patients with ASA physical status I and II, requiring general anaesthesia for elective surgery
Exclusion criteria
Exclusion criteria: 1. Pre-existing adrenal disease / adrenocortical insufficiency 2. Receiving / History of receiving steroids within the last 3 months 3. Sepsis 4. Seizure disorder 5. Hypersensitivity to Etomidate 6. Patients undergoing Emergency surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of priming dose technique, slow injection of induction dose technique and a combination of priming with slow injection technique in preventing etomidate induced myoclonus.Timepoint: Time of onset of myoclonus from induction and duration of myoclonus. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare in all the groups i) The grade of pain on injection ii) The effect on haemodynamic parameters of heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure and peripheral oxygen saturation.Timepoint: 0 min, induction, 1 min, 2 min, 3 min, 4 min, 5 min, 6 min, intubation, 1 min post intubation, 2 min post intubation, 5 min post intubation | — |
Countries
India
Contacts
Public ContactDr Geetha CR
M S Ramaiah Medical College
Outcome results
None listed