Skip to content

Thyroid hormone abnormality to be seen in children whose heart is not able to pump blood properly to rest of the body part.

Thyroid function status in children with congestive heart failure.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/03/032417
Enrollment
72
Registered
2021-03-30
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Q209- Congenital malformation of cardiacchambers and connections, unspecified Health Condition 2: I508- Other heart failure

Interventions

None listed

Sponsors

Maulana Azad Medical College and Associated Lok Nayak Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children (age 6weeks to 60 months) with cyanotic or acyanotic heart disease with congestive heart failure presenting to Department of Pediatrics, MAULANA AZAD MEDICAL COLLEGE AND ASSOCIATED LOK NAYAK HOSPITAL, New Delhi.

Exclusion criteria

Exclusion criteria: 1. Children with past history of thyroid disease (congenital hypothyroidism) or history of intake of thyroxine in last 3months. 2. Children with congenital anomalies like Down Syndrome, Williams-Beuren syndrome or other associated syndromes who are predisposed to underlying thyroid disease. 3. Children with history of birth asphyxia or hypoxic-ischemic encephalopathy (HIE). 4. Children with cardiomyopathy or myocarditis.

Design outcomes

Primary

MeasureTime frame
Proportion of sick euthyroid illness in children having congenital heart disease with congestive heart failure.Timepoint: from initial period of illness till sample taken for investigations.

Secondary

MeasureTime frame
1. Correlation between serum free T3, free T4, TSH and cardiac contractility (ejection fraction). 2. Correlation between serum free T3, free T4, TSH with serum NT pro-BNP levels. 3. Duration of hospitalization in hospitalized children with and without sick euthyroid illness. Timepoint: from initial period of illness till sample taken for investigations.

Countries

India

Contacts

Public ContactBiswajit Sahoo

Maulana Azad Medical College and Associated Lok Nayak Hospital

dr.aashimagupta@gmail.com9868479647

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026