Health Condition 1: Q209- Congenital malformation of cardiacchambers and connections, unspecified Health Condition 2: I508- Other heart failure
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Children (age 6weeks to 60 months) with cyanotic or acyanotic heart disease with congestive heart failure presenting to Department of Pediatrics, MAULANA AZAD MEDICAL COLLEGE AND ASSOCIATED LOK NAYAK HOSPITAL, New Delhi.
Exclusion criteria
Exclusion criteria: 1. Children with past history of thyroid disease (congenital hypothyroidism) or history of intake of thyroxine in last 3months. 2. Children with congenital anomalies like Down Syndrome, Williams-Beuren syndrome or other associated syndromes who are predisposed to underlying thyroid disease. 3. Children with history of birth asphyxia or hypoxic-ischemic encephalopathy (HIE). 4. Children with cardiomyopathy or myocarditis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of sick euthyroid illness in children having congenital heart disease with congestive heart failure.Timepoint: from initial period of illness till sample taken for investigations. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Correlation between serum free T3, free T4, TSH and cardiac contractility (ejection fraction). 2. Correlation between serum free T3, free T4, TSH with serum NT pro-BNP levels. 3. Duration of hospitalization in hospitalized children with and without sick euthyroid illness. Timepoint: from initial period of illness till sample taken for investigations. | — |
Countries
India
Contacts
Maulana Azad Medical College and Associated Lok Nayak Hospital