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Gene analysis in gum diseases

Association of casp3 (rs 4647602) gene polymorphism with generalised periodontitis in south indians of tamil ethnicity - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/03/032412
Enrollment
290
Registered
2021-03-30
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

None listed

Sponsors

Dr Arya Mitra Loka
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Systemically healthy South Indian subjects with Tamil ethnicity. 2.Periodontal healthy subjects. 3.Generalized periodontitis subjects (According to 2017 World Workshop on Classification of periodontal diseases and conditions).

Exclusion criteria

Exclusion criteria: 1.History of periodontal treatment within the previous six months. 2.Antimicrobial therapy, immunosuppressantâ??s, antibiotics and anti-inflammatory drugs within the previous three months. 3.Smokers and alcoholics. 4.Pregnancy and lactation. 5.Presence of neuropathy, nephropathy, retinopathy and macro vascular complications.

Design outcomes

Primary

MeasureTime frame
To determine qualitatively whether there is a presence of CASP3 (rs4647602) Single Nucleotide Polymorphism in South Indian subjects of Tamil ethnicity.Timepoint: at baseline—

Secondary

MeasureTime frame
To observe genotype and allele frequencies of CASP3 rs4647602 among healthy and generalized Periodontitis subjects.Timepoint: at baseline—

Countries

India

Contacts

Public ContactDr Deepa Ponnaiyan

SRM DENTAL COLLEGE

deepa_ponnaiyan@yahoo.co.in9884358568

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 11, 2026