Study the effect of vitamin D3 and vitamin C on glycemic control and oxidative stress markers in Type-2 Diabetes mellitus patients.

A prospective, open label, 3 arm, parallel group comparative study to evaluate the effect of short term treatment with vitamin Dâ?? and vitamin C on glycemic control and oxidative stress markers in inadequately controlled type-2 diabetes mellitus.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/03/032373

Enrollment

Registered

2021-03-30

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Vitamin D3: ARM A will receive Oral vitamin D3 60000IU per week for 90 days Intervention2: Vitamin C: ARM B will receive Oral vitamin C 500mg once a day for 90 days Control Interventio

Eligibility

Inclusion criteria

Inclusion criteria: 1. Male and female patients between 30-75yrs of age, diagnosed with type-2 diabetes mellitus within last 1 year of collection of data. 2. Receiving oral anti-diabetic medications but does not need insulin within last 1 year i.e. from the date of diagnosis of type-2 diabetes mellitus. 3. Patients with HbA1c value more >7% and

Exclusion criteria

Exclusion criteria: 1. DM other than T2DM. 2. Patients with abnormal liver function tests. 3. Patients with abnormal renal function tests. 4. Patients with cardiovascular or respiratory insufficiency. 5. Acutely ill patients. 6. Pregnant and nursing women.

Design outcomes

Primary

Measure	Time frame
The primary outcome of this study will be reduction in HbAâ??c, which is the primary measure of glycaemic control.Timepoint: reduction in HbAâ??c during the period from day 0 to day 90	—

Secondary

Measure	Time frame
The secondary outcomes will be decrease in oxidative stress and thereby decrease in the development of complications in patients with T2DM.Timepoint: Reduction in oxidative stress markers during the period from day 0 to day 90	—

Countries

India

Contacts

Public ContactShingare Sujata Prakash

BYRAMJEE JEEJEEBHOY GOVERNMENT MEDICAL COLLEGE AND SASSOON GENERAL HOSPITALS, PUNE

drsujeet22@gmail.com9822845948

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026