Health Condition 1: O140- Mild to moderate pre-eclampsia
Conditions
Interventions
Intervention1: Vit C (1000 MG) and Vit E (400 IU) and Placebo: 1000 mg of Vitc and 400 IU of Vit E
Route of administration-oral
Frequency of administration- once daily
Control Intervention1: Placebo:
Sponsors
JIPMER pONDICHERRY
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria: Pregnant women presenting in antenatal clinic of JIPMR between 14- 22 weeks of gestation with one or more risks factors a. preeclampsia/eclampsia in previous pregnancy, b. chronic hypertension, c. renal disease, d. HELLP syndrome in prior pregnancy, e. pregestational diabetes, f. women with BMI 30 kg/m2, g. antiphospholipid syndromes, h. multifetal pregnancy, i. thrombophilia, j. Assisted reproductive technique conception, k. age more than 35 years
Exclusion criteria
Exclusion criteria: B. Exclusion criteria: 1. Pregnant women less than 18 years 2. Women with known cardiac lesion 3. Women with known chronic respiratory disease (Tuberculosis, COPD, Bronchial asthma) 4.Women receiving warfarin therapy 5.Women unable to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measure includes incidence of preeclampsia/eclampsia, early onset preeclampsia.Timepoint: in third trimester of pregnancy, and early postpartum period | — |
Secondary
| Measure | Time frame |
|---|---|
| Maternal and fetal complications Systolic and Diastolic functionTimepoint: pregnancy and postpartum period | — |
Countries
India
Contacts
Public ContactDr Nivedita
JIPMER, Puducherry
Outcome results
None listed