To compare two standard surgeries for patients with problem in the innermost layer of the cornea, by replacing the diseased corneal inner layer with a donor cornea, by varying the thickness in the corneal layer being transplanted

Pre Descemets Endothelial Keratoplasty Vs Descemets Membrane Endothelial Keratoplasty: A pilot prospective comparative study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/03/032339

Enrollment

Registered

2021-03-26

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H181- Bullous keratopathy Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: outcomes for 2 standard surgeries namely Descemets Membrane Endothelial Keratoplasty (DMEK) and Pre Descemets Membrane Endothelial keratoplasty are compared : patients with pseudophaki

Eligibility

Inclusion criteria

Inclusion criteria: age >18 years with pseudophakic bullous keratopathy or Fuchs endothelial dystrophy corneal thickness willing to give consent and willing to follow up

Exclusion criteria

Exclusion criteria: corneal stromal scarring corneal astigmatism >6D poor AC visibility posterior segment pathology not willing for consent or follow up

Design outcomes

Primary

Measure	Time frame
Best Corrected Visual Acuity (BCVA)Timepoint: at the end of 6 month	—

Secondary

Measure	Time frame
corneal endothelial specular countTimepoint: at the end of 6 month	—

Countries

India

Contacts

Public ContactDr S CHANDRADEVI

AIIMS

namrata.sharma@gmail.com01126593144

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026