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To assess how best to give oxygen to patients during attempts of intubation: A randomized controlled trial.

Efficacy of high flow nasal oxygen therapy with FIO2:100% and FIO2:60% in comparison with conventional flow oxygen during intubation in adults: A randomized controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/03/032294
Enrollment
72
Registered
2021-03-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Intervention1: High flow nasal oxygen therapy with Fio2:100% during intubation: In group A by high flow nasal oxygen at 60 l/min at FiO2 of 100% preoxygenation and co oxygenation done Intervention2: H

Sponsors

All India Institute of Medical Sciences Patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients scheduled for General Anaesthesia ASA I and II

Exclusion criteria

Exclusion criteria: ASA III/IV Any history of recent or past respiratory disease History of presence of nasal pathology Any anticipated difficult airway defined as: -Modified Mallampati Grade 3 or 4 -Thyro-mental distance less than 6.5 cm -Mouth opening less than 4 cm Patient refusal to take part in the study Obesity(BMI more than or equal to 30) Pregnancy

Design outcomes

Primary

MeasureTime frame
Assessment of time taken for saturation to fall to 94% or below, after administering muscle relaxant.Timepoint: Once saturation falls to 94% after administration of muscle relaxant or 10 minutes after giving muscle relaxant, whichever is earlier.—

Secondary

MeasureTime frame
Analyse the arterial carbon dioxide rate of accumulation from baseline till the point when oxygen saturation reaches 94% or at 10 minutes after muscle relaxant administration if saturation remains above 94% throughout.Timepoint: Once saturation falls to 94% after administration of muscle relaxant or at 10 minutes after giving muscle relaxant, whichever is earlier.;Assessment of arterial oxygen partial pressures when arterial haemoglobin saturation reaches 94% or at 10 minutes after muscle relaxant administration if saturation remains above 94% throughout.Timepoint: Once saturation falls to 94% after administration of muscle relaxant or 10 minutes after giving muscle relaxant, whichever is earlier.;Compare PaO2 levels just after preoxygenation i.e. just before IV anaesthetic administration.Timepoint: 5 minutes after start of experiment.—

Countries

India

Contacts

Public ContactDr Nishant Sahay

All India Institute of Medical Sciences,Patna

nishantsahay@gmail.com9431184516

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026