Health Condition 1: C530- Malignant neoplasm of endocervix
Conditions
Interventions
None listed
Sponsors
Manipal Academy of higher education
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for the phase-1 study: All physically and mentally competent sexually exposed married women with cervico-vaginal intraepithelial neoplasias (CIN) or histologically confirmed cervical squamous cell cancers and retro-positive women with or without cytological abnormalities and women attending routine check-ups will be enrolled. Inclusion criteria for the phase-2 study: Age group between 18 to 45 years who can complete the questionnaires in English or Kannada.
Exclusion criteria
Exclusion criteria: Exclusion criteria for the phase-1 study: Pregnant women, Women below 30 years, and women above 65 years of age, except those with diagnosed cancer cervix, where irrespective of age, women will be included, Women with auto-immune diseases, Women who previously received immunosuppressive treatment, radiotherapy, or chemotherapy, Women with a history of taking anti-inflammatory drugs within two weeks before sampling, Women who are actively taking oral contraceptives. Exclusion criteria for the phase-2 study: Pregnant women, women with history of hysterectomy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Our study will give information about immunological profile of genital HPV infected immunocompetent women and women having concurrent HIV infection Timepoint: 3 years | — |
Secondary
| Measure | Time frame |
|---|---|
| This study is expected to provide a sound rationale for decision making with respect to vaccination.Timepoint: 2 | — |
Countries
India
Contacts
Public ContactDr Revathi P Shenoy
Manipal academy of higher education
Outcome results
None listed