A clinical trial to study effect of two drugs,sublingual misoprostol and intravenous Trenaxamic acid in primary lower segment cesarean section patients to estimate the amount of blood loss

To study efficay of sublingual Misoprostol vs intravenous Tranexamic acid in reducing amount of blood loss in full term pregnant women undergoing primary LSCS :A randomized control trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/03/032275

Enrollment

140

Registered

2021-03-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O94-O9A- Other obstetric conditions, not elsewhere classified

Interventions

Intervention1: Tab Misoprostol: Single dose of Tab Misopostol 600mcg sublingually just before incision of anterior abdominal wall Control Intervention1: INJECTION TRANEXAMIC ACID: Single dose of Injec

Eligibility

Inclusion criteria

Inclusion criteria: Full term women undergoing primary Cesarean Section at Aarupadi Veedu Medical College and Hospital who are willing to participate

Exclusion criteria

Exclusion criteria: 1)Previous Cesarean Section 2)Induced/augmented labour 3)obesity 4)chorioamnionitis 5)antepartum hemorrhage 6)pre term pregnancy 7)overdistension-multipregnancy,polyhydromnios

Design outcomes

Primary

Measure	Time frame
amount of blood loss pre operatively (hematocrit) amount of blood loss post operatively(hematocrit)Timepoint: within 1 week of cesarean section	—

Secondary

Measure	Time frame
safety, side effects, cost effectivenessTimepoint: within 1 week of cesarean section	—

Countries

India

Contacts

Public ContactDr NIKHITHA B

AARUPADAI VEEDU MEDICAL COLLEGE AND HOSPITAL

pushpakotur@gmail.com9449287811

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026