Comparing the effective post-operative onset of pain effect of two drug combinations Bupivacaine with Fentanyl and Bupivacaine with Dexmedetomidine in lower limb surgeries

A Comparative study of Post-operative Analgesic Effect of Intrathecal Bupivacaine with Fentanyl versus Intrathecal Bupivacaine with Dexmedetomidine in lower limb surgeries-A Double Blind Randomized Controlled study - CPOAEITBFVBDLLS

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/03/032274

Enrollment

120

Registered

2021-03-24

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: M858- Other specified disorders of bonedensity and structure

Interventions

Intervention1: Spinal Anesthesia with Bupivacaine: Spinal Anesthesia is the choice of regional Anesthesia for lower limb Orthopedic and General Surgery procedures. Control Intervention1: Fentanyl and

Eligibility

Inclusion criteria

Inclusion criteria: Patients of age 18-65yrs of either sex Orthopedic and General Surgeries lasting for 1-2 hrs Patients of ASA-I & II Patients weighing 50-80kgs.

Exclusion criteria

Exclusion criteria: Hypersensitivity to any of the drugs Uncontrolled Diabetes Mellitus and Hypertension Renal and Liver failures Cardiac dysrhythmias Coagulopathies

Design outcomes

Primary

Measure	Time frame
To compare Post-operative Pain Analgesia of Intrathecal Bupivacaine with Fentanyl versus Intrathecal Bupivacaine with DexmedetomidineTimepoint: 12 HOURS	—

Secondary

Measure	Time frame
Sensory blockade Motor blockade Timepoint: Sensory-8hrs Motor-8hrs	—

Countries

India

Contacts

Public ContactDr V Ezhilrajan

Aarupadai Veedu Medical college & Hospital,Pondicherry

ezhilrajan96@gmail.com9843030074

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026