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Comparative study of Conventional oxygen therapy, Non-invasive ventilation and High flow nasal cannula in COPD patients undergoing bronchoscopy

A prospective comparative study of Conventional oxygen therapy, Non-invasive ventilation and High flow nasal cannula in COPD patients undergoing bronchoscopy - NICOBAR

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/03/032190
Enrollment
90
Registered
2021-03-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J449- Chronic obstructive pulmonary disease, unspecified

Interventions

Intervention1: Non Invasive Ventilation (NIV) and High Flow Nasal Canula (HFNC): NIV Group: Patients assigned to NIV group will be connected to the ventilator (Bellavista 1000 ICU NIV) through a clear

Sponsors

Post Graduate Institute of Medical Sciences PGIMS Rohtak
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Willing to give valid consent COPD patients undergoing bronchoscopy

Exclusion criteria

Exclusion criteria: Receiving HFNC before randomization Nasal deformity or packing precluding HFNC use Myocardial infarction (within 3 months) Altered Sensorium Heart rate below 50 beats/minute Hemodynamic instability with systolic arterial blood pressure below 90 mm Hg Respiratory rate above 35 breaths/minute despite oxygen therapy Arterial pH Facial surgery, trauma and any other contraindication for NIV Those on home NIV

Design outcomes

Primary

MeasureTime frame
To compare the lowest recorded SpO2(pulse oximeter oxygen saturation) during bronchoscopy among the patients of COPD receiving conventional oxygen therapy, NIV and HFNCTimepoint: At Baseline, During Bronchoscopy and at 1 hour of Bronchoscopy completion—

Secondary

MeasureTime frame
1. Absolute arterial carbon dioxide tension (PaCO2) and change in PaCO2 from baseline 2. Changes in cardiovascular parameters [systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR)] from the baseline 3. Patient related comfort 4. Incidence of adverse eventsTimepoint: At Baseline, During Bronchoscopy and at 1 hour of Bronchoscopy completion—

Countries

India

Contacts

Public ContactVINOD KUMAR SHARMA

Pt. B.D. Sharma PGIMS, Rohtak

dhruvachaudhry@yahoo.co.in9416051616

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 8, 2026