Skip to content

To assess the effect of two days injectable dexamethasone therapy in resolution of uncomplicated parapneumonic effusion in hospitalized children aged 1month to 14years

To assess the effect of two days injectable dexamethasone therapy in resolution of uncomplicated parapneumonic effusion in hospitalised children aged 1month to 14years- A single blinded randomised trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/03/032169
Enrollment
60
Registered
2021-03-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J681- Pulmonary edema due to chemicals,gases, fumes and vapors

Interventions

Intervention1: Dexmethasone: intravenous Dexamethasone 0.25mg/kg/dose every 6 hours over a period of 48 hours along with routine antibiotics for pneumonia Control Intervention1: No placebo given, only

Sponsors

Department of Paediatrics
Lead Sponsor
Department of Radiodiagnosis
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Children aged 1mo-14years 1 Children admitted for pneumonia with uncomplicated parapneumonic effusion confirmed by bedside ultrasonography 2 Patients whose parents give consent for participation

Exclusion criteria

Exclusion criteria: • Immmune deficiency state • Malignancy • Fluid collection due to congestive heart failure,nephrotic syndrome,liver disease and tuberculosis • Patients with complicated pleural effusion • Patients with hemodynamic/respiratory instability requiring intensive care • Patients taking steroids in any form due to any disease

Design outcomes

Primary

MeasureTime frame
To assess the effect of two days injectable dexamethasone therapy in resolution of uncomplicated parapneumonic effusion that is the decrease in quantity of parapneumonic effusion after two days of injectable Dexamethasone therapy in hospitalized children aged 1month-14years as defined by bedside ultrasonographyTimepoint: To assess the effect of two days injectable dexamethasone therapy in resolution of uncomplicated parapneumonic effusion that is the decrease in quantity of parapneumonic effusion after two days of injectable dexamethasone therapy in hospitalized children aged 1month-14years as defined by bedside ultrasonography

Secondary

MeasureTime frame
â?¢ To determine change in CRP level 72hrs after initiation of dexamethasone therapy.Timepoint: 72 hours

Countries

India

Contacts

Public ContactShally Awasthi

King Georges Medical University Lucknow

shally07@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026