Skip to content

Neurophysiological method to predict the relapse in patients with alcohol dependence

Event related potential markers of craving as predictors of relapse in patients with alcohol dependence. - Nil

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/03/032163
Enrollment
150
Registered
2021-03-19
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

None listed

Sponsors

Dhirubhai Ambani Foundation
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Alcohol dependent patients: i.Patients fulfilling the diagnostic criteria for alcohol dependence according to ICD-10 DCR (World Health Organization, 1993) ii. Age range: 18 â?? 55 years iii. Male patients iv. Patients willing to participate in the study v.Right-handed vi.5 years of formal education Healthy controls: I. Male ii. Age range: 18 â?? 55 years iii. General Health Questionnaire 5 score iv. 5 years of formal education

Exclusion criteria

Exclusion criteria: Alcohol dependent patients: i. Harmful use of any other psychoactive substance other than nicotine or caffeine. (Campanella et al .,2020) ii. HMSE score iii. Significant visual impairment (refractory errors, color blindness ,6/6 vision) iv. Presence of any chronic physical illness (hepatic encephalopathy, chronic renal disease, uncontrolled diabetes mellitus, thyroid disorders) v. Presence of any chronic neurological illness (epilepsy, traumatic brain injury, stroke, degenerative disorders) Healthy controls: i. Diagnosis of a psychiatric disorder ii. Presence of any medical or neurological illness iii. Presence of any family history of psychiatric disorder iv. HMSE score v. Left-handedness

Design outcomes

Primary

MeasureTime frame
1.Study will provide specific neurophysiological marker of craving to predict relapse based on ERP findings. 2.Study will provide an objective measure of craving compared to self-report of craving. 3.At the clinical level, the study would be relevant as monitoring changes in these neuro -cognitive indicators would help to objectively identify patients â??at risk ? and thereby assign them to specific neuro- cognitive rehabilitation services.Timepoint: 3 years

Secondary

MeasureTime frame
1.Study will provide an objective measure of craving compared to self-report of craving. 2.At the clinical level, the study would be relevant as monitoring changes in these neuro -cognitive indicators would help to objectively identify patients â??at risk ? and thereby assign them to specific neuro- cognitive rehabilitation services.Timepoint: 3 years

Countries

India

Contacts

Public ContactAnupa A Shenoy

Kasturba Medical College, Manipal

samir.kp@manipal.edu8971086304

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026