Health Condition 1: 8- Other Procedures
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Alcohol dependent patients: i.Patients fulfilling the diagnostic criteria for alcohol dependence according to ICD-10 DCR (World Health Organization, 1993) ii. Age range: 18 â?? 55 years iii. Male patients iv. Patients willing to participate in the study v.Right-handed vi.5 years of formal education Healthy controls: I. Male ii. Age range: 18 â?? 55 years iii. General Health Questionnaire 5 score iv. 5 years of formal education
Exclusion criteria
Exclusion criteria: Alcohol dependent patients: i. Harmful use of any other psychoactive substance other than nicotine or caffeine. (Campanella et al .,2020) ii. HMSE score iii. Significant visual impairment (refractory errors, color blindness ,6/6 vision) iv. Presence of any chronic physical illness (hepatic encephalopathy, chronic renal disease, uncontrolled diabetes mellitus, thyroid disorders) v. Presence of any chronic neurological illness (epilepsy, traumatic brain injury, stroke, degenerative disorders) Healthy controls: i. Diagnosis of a psychiatric disorder ii. Presence of any medical or neurological illness iii. Presence of any family history of psychiatric disorder iv. HMSE score v. Left-handedness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Study will provide specific neurophysiological marker of craving to predict relapse based on ERP findings. 2.Study will provide an objective measure of craving compared to self-report of craving. 3.At the clinical level, the study would be relevant as monitoring changes in these neuro -cognitive indicators would help to objectively identify patients â??at risk ? and thereby assign them to specific neuro- cognitive rehabilitation services.Timepoint: 3 years | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Study will provide an objective measure of craving compared to self-report of craving. 2.At the clinical level, the study would be relevant as monitoring changes in these neuro -cognitive indicators would help to objectively identify patients â??at risk ? and thereby assign them to specific neuro- cognitive rehabilitation services.Timepoint: 3 years | — |
Countries
India
Contacts
Kasturba Medical College, Manipal