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EFFECTIVENESS OF CONVENTIONAL MRI AND DIFFUSION TENSOR IMAGING TO PROGNOSTICATE OUTCOME OF SURGICALLY TREATED CERVICAL MYELOPATHY PATIENTS

PROGNOSTIC VALUE OF CONVENTIONAL MRI AND DIFFUSION TENSOR IMAGING IN SURGICALLY TREATED DEGENERATIVE CERVICAL MYELOPATHY PATIENTS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/03/032148
Enrollment
66
Registered
2021-03-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M500- Cervical disc disorder with myelopathy

Interventions

Intervention1: Surgery: 1.anterior cervical discectomy and fusion 2. anterior cervical corpectomy and fusion 3. laminectomy +/- lateral mass/pedicle screw fixation. 4. Laminoplasty

Sponsors

INK institute of neurosciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • >18 years. • Elective cervical surgery for cervical compressive myelopathy (due to spondylosis or ossified posterior longitudinal ligament) with evidence of cord compression in radiological imaging with correlating clinical features of myelopathy or myeloradiculopathy.

Exclusion criteria

Exclusion criteria: • Patients scheduled for revision procedures. • Patients undergoing surgical procedures for traumatic, neoplastic, or infectious indications. • Patients in whom MRI is contraindicated.

Design outcomes

Primary

MeasureTime frame
To find the predictive values of MRI parameters like the compression ratio (CR) , transverse area (TA), and signal intensity ratio (SIR) and DTI parameters like - apparent diffusion coefï¬?cient (ADC) and fractional anisotropy (FA) Relative anisotropy (RA), Volume ratio (VR) on clinical improvement (JOA score)in Degenerative cervical myelopathy of the spinal cord. The final JOA score will be used calculate clinical improvement.Timepoint: JOA score will be calculated preoperative, 1,2 and 3 months postoperative—

Secondary

MeasureTime frame
1. Clinical outcome measure using difference in Nurick scale. 2. To calculate change in signal intensity ratio (SIR), apparent diffusion coefï¬?cient (ADC) and fractional anisotropy (FA) Relative anisotropy (RA), Volume ratio (VR) pre and post operatively and check for correlation with clinical improvement (JOA score). 3. Difference of Neck Disability Index questionnaire score and a visual analogue scale for pain.Timepoint: preoperative, 1 , 2 , 3 months post operative—

Countries

India

Contacts

Public ContactV SELVIN PRABHAKAR

I-NK institute of neurosciences

dr.selvinprabhakar@gmail.com09500029431

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026