Health Condition 1: K50- Crohns disease [regional enteritis] Health Condition 2: K51- Ulcerative colitis
Conditions
Interventions
Intervention1: Fecal Microbiota Transplantation: A freshly collected sample will be inspected visually and formed stools (Bristol stool scale, 3 and 4) with no obvious blood or mucous will be accepted
Seward Ltd, Worthing, UK) till it reaches a liquid consistency. Universal precautions will be observed and separate disposable bags will be used for each patient. The particulate matter will be filter
Sponsors
Dayanand Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients with IBD aged � 18 years at the time of enrolment Written informed consent to participate
Exclusion criteria
Exclusion criteria: Age Pregnancy Known HIV positive. Disseminated or advanced malignancy. Concomitant severe underlying systemic illness that in the opinion of the investigator would interfere with completion of follow-up. Active drug use or dependence that, in the opinion of the study investigator, would interfere with adherence to study requirements. Any other condition, which in the opinion of the investigator would impede compliance or hinder completion of study. Inability to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the efficacy of faecal microbiota transplantation (FMT) in ulcerative colitis To study the efficacy of faecal microbiota transplantation (FMT) in Crohnââ?¬â?¢s disease Timepoint: 4 weeks, 12 weeks, 24 weeks, 52 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the efficacy and safety of FMT in pouchitis and extra-intestinal manifestations of IBD.Timepoint: 4 weeks, 12 weeks, 24 weeks, 52 weeks;To study the microbiota profile of the donors and FMT recipients pre and post FMT and compare with the donor microbiota profileTimepoint: 4 weeks, 12 weeks, 24 weeks, 52 weeks;To study the safety of FMT in ulcerative colitis and crohnââ?¬â?¢s disease Timepoint: 4 weeks, 12 weeks, 24 weeks, 52 weeks | — |
Countries
India
Contacts
Public ContactAjit Sood
Department of Gastroenterology Third Floor Dayanand Medical College and Hospital Ludhiana
Outcome results
None listed