Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Elective Brian And Spine Surgery Patients: Pre-operative hippocampal volume measured with mri and duration of emergence from general anaesthesia
Control Intervention1: Elective Brian An
Sponsors
Indian Council of Medical Research ICMR
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients above the age of 18 years who are scheduled for elective neurosurgical procedures under general anaesthesia 2. Patients having preoperative MRI Brain [T1-MPRAGE sequence] 3. GCS of 15
Exclusion criteria
Exclusion criteria: 1.Patients with a. Hypothyroidism b. GCS c. Emergence time beyond 1 hour after discontinuing anaesthesia [8] 2.Patients having excision of hippocampus and amygdala. 3. Patients with temporal lobe pathology 4. Brain MRI [performed for the purpose of research] in patients undergoing spine surgery showing incidental brain pathology
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the correlation between preoperative hippocampus volume and duration of emergence after general anaesthesiaTimepoint: 1 hour after the end of anaesthesia | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the relationship between preoperative hippocampus volume and functional reserve of the patient with the time and pattern of emergence after general anaesthesia Timepoint: 1 hour during recovery;To evaluate if there exists a gender difference in patterns of emergenceTimepoint: 1 hour during recovery | — |
Countries
India
Contacts
Public ContactDr K Pramod
National Institute of Mental Health and Neurosciences
Outcome results
None listed