A Comparative Clinical study of Shatvariyadi churna and Brahmi ghrita Nashya in the management of menopausal symptoms.

A Comparative Clinical study of the efficacy of Shatvariyadi churna and Brahmi ghrita Nashya in the management of Rajoniviritti Janya Laksana w.s.r Menopausal syndrome - CCESCBNMRL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/03/032119

Enrollment

Registered

2021-03-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N951- Menopausal and female climactericstates

Interventions

Intervention1: Shatavariyadi churna: Dose- 5gm of Shatavariyadi churna orally twice a day with milk for 3 consecutive month. Control Intervention1: Shatavariyadi churna orally and Brahmi ghrita nasya

Eligibility

Inclusion criteria

Inclusion criteria: 1. Amenorrhea for 12 months or more. 2. women age group 45-60 years. 3. Women is not undergoing any estrogen replacement therapy presently and also not for last 6 Months for menopausal symptoms. 4. Subjects taking medication for HTN, D.M, if she had, should be controlled. 5. Subjects fulfilling the inclusion criteria. 6. Subjects willing to participate in this trial.

Exclusion criteria

Exclusion criteria: 1. Women with Surgical menopause. 2. Patient with evidence of Malignancy. 3. Patient with uncontrolled Diabetes Mellitus. 4. Patient who have a past history of Heart disease like Atrial Fibrillation , Coronary artery disease (CAD), Acute coronary Syndrome ,MI , Stroke , Heart failure etc. 5. Patient with poorly controlled Hypertension. 6. Patient on prolonged medication ( >6 months) with Hormone Replacement Therapy ( HRT) corticosteroids , Antidepressant , etc or any other drugs that may have an influence on the outcome of study. 7. Patient with concurrent serious hepatic disorders , Renal pathology. 8. Patient with severe Pulmonary Dysfunction . 9. Patient undergoing any kind of Chemotherapy , Radiotherapy. 10. Subjects who not willing to participate in the study

Design outcomes

Primary

Measure	Time frame
1.To evaluate the efficacy of Shatavariyadi churna with Brahmi ghrita nashya in management of Rajo niviritti janya laksana w.s.r to Menopausal syndrome. 2.To assess the efficacy of trial therapy on the subjective parameters like Hot flushes, Nights sweats, Fatigue, Palpitation, Weakness ,Insomnia ,Irritability Anxiety, Mood swing, Depression and objective parameters are blood CBC ,RBS ,Urine â?? R/M, Thyroid profile, USG. Timepoint: Final assessment will be done after completion of trial of 4 consecutive months (3 months with clinical therapy and 1 month drug free)	—

Measure

Time frame

1.To evaluate the efficacy of Shatavariyadi churna with Brahmi ghrita nashya in management of Rajo niviritti janya laksana w.s.r to Menopausal syndrome. 2.To assess the efficacy of trial therapy on the subjective parameters like Hot flushes, Nights sweats, Fatigue, Palpitation, Weakness ,Insomnia ,Irritability Anxiety, Mood swing, Depression and objective parameters are blood CBC ,RBS ,Urine â?? R/M, Thyroid profile, USG. Timepoint: Final assessment will be done after completion of trial of 4 consecutive months (3 months with clinical therapy and 1 month drug free)

—

Secondary

Measure	Time frame
To assess the efficacy of trial therapy on subjective parameters like Hot flushes, Nights sweats, Fatigue, Palpitation ,Weakness, Insomnia Irritability, Anxiety, Mood swing, Depression on the management of Menopausal syndrome. Timepoint: Follow up- Each month during trial.	—

Countries

India

Contacts

Public ContactDr Himanshi singh

State Ayurvedic College and Hospital

bedar.shashi@gmail.com8795545443

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026