Health Condition 1: K137- Other and unspecified lesions of oral mucosa
Conditions
Interventions
Control Intervention1: Not applicable: Not applicable
Sponsors
Kiran Kumar
Eligibility
Inclusion criteria
Inclusion criteria: 1.OSCC patients who are undergoing treatment by Radical Neck Dissection or Modified Radical Neck Dissection of with or without adjunct radiotherapy. 2.OSCC patients who have undergone Radical Neck Dissection of lesion with or without adjunct radiotherapy reported back to hospital with loco-regional recurrences of tumour are considered as recurrent cases of OSCC. 3.OSCC patients who have undergone Radical Neck Dissection of lesion with or without adjunct radiotherapy and are disease free for at least 3 years are considered as non-recurrent cases of OSCC.
Exclusion criteria
Exclusion criteria: 1.Patients with neo-adjuvant chemo-radiotherapy 2.Patients with perioperative death 3.Patients suffering from immunodeficiency conditions like HIV/AIDS and other malignancies. 4.Patients suffering from known nutritional deficiencies. 5.Patients with distant metastasis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Present study will be carried out on large cohort of 100 Oral Squamous Cell Carcinoma cases, 30 normal mucosa and multivariate survival analysis will be done after adjusting the clinic-pathological parameters to analyze the prognostic ability of LncRNA.Timepoint: 3 years from March 2021 to March 2023 | — |
Secondary
| Measure | Time frame |
|---|---|
| The present study will examine the reliability of LncRNA detection in formalin fixed paraffin tissue blocks compared to paired fresh tissue samplesTimepoint: one year from March 2021 to March 2022 | — |
Countries
India
Contacts
Public ContactKiran Kumar
SDM college of Dental Sciences and Hospital
Outcome results
None listed