Study of ketamine gargle for relieving sore throat after surgeries under general anaesthesia

Evaluation of ketamine gargle for post - operative sore throat in patients undergoing general anaesthesia with endotracheal intubation.

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/03/032075

Enrollment

Registered

2021-03-17

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: K318- Other specified diseases of stomach and duodenum

Interventions

Intervention1: Comparative study between ketamine gargle & normal saline gargle on post operative sore throat after intubation: Evaluation of ketamine gargle for post operative sore throat in patients

Eligibility

Inclusion criteria

Inclusion criteria: The study will be conducted on patients of either gender , between 18-65 years of age belonging to American College of Anaesthesiologists ( ASA ) physical status I & II undergoing elective laparoscopic surgery under general anaesthesia with endotracheal intubation

Exclusion criteria

Exclusion criteria: 1.] Patients with difficult airway 2.) Patients with a history of pre - operative sore throat , oral surgeries, asthma, diabetes. 3.) Patients with known allergies to study drug and rescue drugs. 4.) Patients consuming non - steroidal anti - inflammatory drugs or topical steroids within 24 hrs prior to surgery 5. ) Duration of surgery less than 1 hr and more than 4 hours.

Design outcomes

Primary

Measure	Time frame
To evaluate the incidence and severity of post - operative sore throat in patients receiving pre operative gargle with 50 mg of ketamine ( 1 ml ) in 29 ml normal saline undergoing elective laparoscopic surgery under general anaesthesia with endotracheal intubationTimepoint: Patient followed up for post operative sore throat at 0,2,4,24 hrs after extubation.	—

Secondary

Measure	Time frame
To evaluate the incidence and severity of cough and hoarseness of voice in patients receiving pre operative gargle with 50 mg of ketamine ( 1 ml ) in 29 ml normal saline undergoing elective laparoscopic surgery under general anaesthesia with endotracheal intubationTimepoint: Patient followed up for cough and hoarseness of voice at 0,2,4,24 hrs after extubation.	—

Countries

India

Contacts

Public ContactAswin Sanjeevan

Vardhman Mahavir Medical College and Safdarjung Hospital

shruti.anaesth@gmail.com9212308441

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026