Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Lidocaine: Intravenous(IV) Lidocaine 1.5mg/kg 90s before induction followed by 2 mg/kg/hr maintenance infusion of 20mg/ml
Control Intervention1: 0.9% Normal Saline: 0.9% Normal Saline i
Sponsors
Post Graduate Institute of Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anesthesiologists(ASA) 1-2; Age 18-60 females; posted for elective total mastectomy; requiring general anaesthesia
Exclusion criteria
Exclusion criteria: uncompensated pulmonary, neurological, hepatic, renal (Creatinine clearance <30ml/min), endocrinological (thyroid/ cortisol dysfunctions) diseases, systemic illness, allergy/ hypersensitivity to lidocaine, any drug dependence or substance abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Propofol requirement during CLADS controlled anaesthesiaTimepoint: Intraoperative | — |
Secondary
| Measure | Time frame |
|---|---|
| Analgesic requirementTimepoint: Postoperative till 4 hours;Emetic episodesTimepoint: Postoperative till 4 hours;Fentanyl requirement during CLADS controlled anaesthesiaTimepoint: Intraoperative;Other significant adverse effectsTimepoint: Postoperative till 4 hours;Variability of hemodynamicsTimepoint: intraoperative | — |
Countries
India
Contacts
Public ContactJijo Francis
Post Graduate Institute of Medical Education and Research
Outcome results
None listed