To compare the Antimicrobial Action of Nanosilver Solution, Azadirachta indica, Sodium Hypochlorite and Normal Saline as Root Canal Irrigants in Primary Teeth

Comparative Evaluation of Antimicrobial Efficacy of Nanosilver Solution, Azadirachta indica, Sodium Hypochlorite and Normal Saline as Root Canal Irrigants in Primary Teeth

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/03/032026

Enrollment

Registered

2021-03-16

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: Nanosilver solution: The solution contains Nano silver particles . 1 mL of solution will be delivered into the root canal for 3-5 seconds on first appointment Control Intervention1: Aza

Eligibility

Inclusion criteria

Inclusion criteria: Pulpally involved teeth with atleast 2/3rd of total root length remaining and requiring endodontic treatment.

Exclusion criteria

Exclusion criteria: Grossly decayed teeth with root resorption of more than 2/3rd of total root length Teeth indicated for extraction Medically compromised children

Design outcomes

Primary

Measure	Time frame
To determine and assess the microbial count in infected root canals of primary teeth at baseline and after irrigation with Nanosilver Solution, Azadirachta indica, Sodium Hypochlorite and Normal Saline Timepoint: 1 week	—

Secondary

Measure	Time frame
To observe and compare the change in microbial count after irrigation with Nanosilver Solution, Azadirachta indica, Sodium Hypochlorite and Normal Saline in infected root canals of primary teethTimepoint: 1 week	—

Countries

India

Contacts

Public ContactDr Nidhi Agarwal

Institute of Dental Studies and Technologies

doc.nagarwal@gmail.com9871262302

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026