Health Condition 1: K811- Chronic cholecystitis
Conditions
Interventions
Intervention1: Intar nasal dexmedetomidine with intravenous dexmedetomidine: None
Intervention2: Dexmedetomidine: Intarnasal 1mcg/kg before induction of anaesthesia. Only one dose
Intervention3: De
Sponsors
none
Eligibility
Inclusion criteria
Inclusion criteria: ASA I and II (American Society of Anaesthesiologists) scheduled for elective laparoscopic surgery were included in the study.
Exclusion criteria
Exclusion criteria: . Exclusion criteria included pregnancy, patients with ejection fraction 60 years ,BMI >30kg/m2, valvular dysfunction , patients taking clonidine or α-methyldopa, patients with insulin dependent diabetes, renal or hepatic dysfunction patients with respiratory disorder, patients with history of CABG and patients in which intubation time was more than 20 seconds
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)To compare and evaluate the efficacy of intranasal and intravenous dexmedetomidine as premedication before general anaesthesiaTimepoint: outcome will be assessed as baseline,t5,t10,t15,t20,t25,t30,t35,t40 where t is the time from intranasal administeration of drug/placebo | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare and evaluate sideeffects with intranasal and intravenous dexmedetomidine as premedicationTimepoint: side effects will be monitored and recorded at t5,t10,t15,t20,t25,t30,t35,t40 from administeration of intranasal study drug/placebo | — |
Countries
India
Contacts
Public ContactPriyanka Gupta
Kasturba Medical college,manipal
Outcome results
None listed