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Treatment for gum diseases using nanoparticles

Efficacy of nanohydroxyapatite in Periodontal regeneration

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/03/032008
Enrollment
20
Registered
2021-03-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Injectable nanohydroxyapatite-nanochitosan bone graft: Injectable Bone graft contains 35% nanohydroxyapatite and 35% nano chitosan particles. Infrabony defects will be filled using this

Sponsors

JSS Academy of Higher Education and Research Institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects with more than 20 remaining teeth Subjects with Chronic Periodontitis with Periodontal pocket depth greater than 5mm Systemically healthy subjects with any vertical bone loss

Exclusion criteria

Exclusion criteria: Pregnant and lactating mothers, smokers Allergic to chitosan/HAP Compromised immune system Undergone periodontal therapy in previous 6 months Subjects taking medication that could interfere with soft tissue/bone healing.

Design outcomes

Primary

MeasureTime frame
Periodontal regenerationTimepoint: Baseline,3,months, 6 months,9months—

Secondary

MeasureTime frame
To reduce Periodontal pocket depthTimepoint: Baseline,3,months, 6 months,9months—

Countries

India

Contacts

Public ContactKalyanam Rashmi Durga

JSS Dental College and Hospital

drsravindra@yahoo.co.in9481872469

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026