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Effect of TPRF, LPRF and Open flap debridement in treating upper and lower jaw bony defects in adult patients with gum diseases

Comparative evaluation of open flap debridement , leukocyte rich platelet rich fibrin and titanium platelet rich fibrin in the treatment of three walled intrabony defects in Stage II and Stage III Periodontitis: A clinical study.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/03/031964
Enrollment
75
Registered
2021-03-15
Start date
Unknown
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K051- Chronic gingivitis

Interventions

Intervention1: Group I,II,III each having 25 sites: Group I-control Group wherein open flap debridement will be done Group II- wherein TPRF is placed at the site Group III- wherein LPRF is placed at

Sponsors

DrGowri Pendyala
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with stage II and stage III Periodontitis with presence of 3 walled intrabony defects of 3mm along with probing depth of 5mm and Clinical Attchment loss greater than or equal to 3mm when evaluated 8 weeks after phase I therapy on atleast 3 teeth

Exclusion criteria

Exclusion criteria: Patients with systemic diseases, blood dyscrasiasis, plaque index >1.5 afetr phase I therapy,pregnant and lactating, alcohol and tobacco consumption, nonvital teeth , mobile and furcation defects

Design outcomes

Primary

MeasureTime frame
bone defect fillTimepoint: 1,3,6,9 months—

Secondary

MeasureTime frame
decrease in Probing depth, gain in clinical attachment level, reduction in plaque index, reduction in modified sulcus bleeding indexTimepoint: 1,3,6,9 months—

Countries

India

Contacts

Public ContactDr Gowri Pendyala

Rural Dental College, Pravara Institute of Medical Sciences

ameetmani2007@rediffmail.com9545612345

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026