THE EFFECT OF DIFFERENT ANAESTHETIC TECHNIQUES ON NEUTROPHIL LYMPHOCYTE RATIO AND PLATELET LYMPHOCYTE RATIO IN PAEDIATRIC SURGERY

Effect of general anaesthesia and subarachnoid block on neutrophil to lymphocyte ratio(NLR) and platelet to lymphocyte ratio(PLR) in paediatric patients undergoing infra umbilical surgeries.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/03/031941

Enrollment

120

Registered

2021-03-12

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: general anaesthesia and subarachnoid block.: Premedication: IV Dexmedetomidine26,27,30,31,32,33 1mcg/kg loading over 10 minutes in preop room with Ramsay Sedation Scoring and

Eligibility

Inclusion criteria

Inclusion criteria: 1) ASA1 & ASA2 Patients. 2) Age between 3-12 years. 3) Patients of both sexes. 4) Infra umbilical surgeries.

Exclusion criteria

Exclusion criteria: Refusal of patients attendant. 2)Patient with any contraindication to spinal anaesthesia. H/O local anaesthetic allergy /hypersensitivity. 3)Malignant condition. 4)Immunodeficiency. 5)Use of anticoagulants. 6)Children with haematological disease. 7)with existing acute infection. 8)endocrine disease. 9)Electrolyte imbalance. 10)Hepatic and renal dysfunctions. 11)H/O chemotherapy and radiotherapy.

Design outcomes

Primary

Measure	Time frame
To investigate the effects of general anaesthesia and subarachnoid block on neutrophil to lymphocyte ratio and platelet lymphocyte ratio in paediatric patients undergoing for infra-umbilical surgeries.Timepoint: 0, 6 and 24 hours	—

Secondary

Measure	Time frame
Post-op complication within 48 hour.Timepoint: Post-op complication within 48 hour.	—

Countries

India

Contacts

Public ContactSHAHNA ALI

JAWAHARLAL NEHRU MEDICAL COLLEGE. AMU, ALIGARH

drshahna.farhan@gmail.com9411979684

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026