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To evaluate the role of electrical cardiometry for assessing response to fluid administration by measuring cardiac output before and after raising the leg in patients with sudden fall in blood pressure or with signs of low blood pressure and to compare it with transthoracic echocardiography

Evaluation of electrical cardiometry to assess fluid responsiveness by tracking PLR-induced change in cardiac output in patients with acute circulatory failure: A comparison study with transthoracic echocardiography

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/03/031921
Enrollment
125
Registered
2021-03-11
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I959- Hypotension, unspecified

Interventions

Intervention1: NIL: NIL

Sponsors

Department of Anaesthesiology Pain Medicine and Critical Care AIIMS NEW DELHI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients (18-65 years) with an arterial catheter in situ, on controlled mechanical ventilation and at least one of the following signs of circulatory failure: 1.systolic blood pressure 50 mm Hg in previously hypertensive patients 2.The requirement of vasopressor drugs 3.urine output 4.Heart rate > 100 beats/minute 5.Presence of skin mottling or delayed capillary refilling ( > 3 seconds)

Exclusion criteria

Exclusion criteria: 1. age 65 years 2. pregnancy 3. patient with arrhythmias 4. known case of heart failure on treatment 5. patients with lower limb amputation 6. patient with valvular heart diseases 7. contraindications to performing PLR (Lower limb DVT, Limb/pelvic fracture, abdominal surgeries, intra-abdominal hypertension, intracranial hypertension 8. presence of wound/dressing in the neck 9. difficulty in getting adequate echo window (morbid obese[BMI > 40 Kg/square metre],chest wall trauma)

Design outcomes

Primary

MeasureTime frame
To measure bias, mean, and limits of agreement for cardiac output obtained with Electrical cardiometry and those obtained by transthoracic echocardiography, before and after passive leg raising in patients with acute circulatory failure.Timepoint: the outcome will be assessed at the end of study period—

Secondary

MeasureTime frame
a. To measure the change in heart rate, systolic, diastolic, mean arterial pressure, and Central venous pressure b. To measure the change in ventilatory parameters (peak airway pressure and mean airway pressure) c. To compare the dose and type of vasoactive drugs in fluid responders and non-responder group Timepoint: before and after passive leg raising—

Countries

India

Contacts

Public ContactShashikant Sharma

All India Institute of Medical Sciences

anjantrikha@gmail.com9810977901

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026