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Evaluation of the effect of gum treatment on saliva and blood fetuin-A levels in patients with gum disease

Evaluation of the effect of scaling and root planing on salivary and serum fetuin-a levels in patients with chronic periodontitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/03/031919
Enrollment
60
Registered
2021-03-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Non-surgical periodontal therapy: Scaling and root planing in one sitting. Recalled after a duration of 3 months Control Intervention1: NIL: NIL

Sponsors

Dr Sanjita Nair
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Presence of at least 20 natural teeth Group 1 healthy individuals having no clinical signs of gingival inflammation, no clinical attachment loss and probing pocket depth less than or equal to 3mm Group 2 patients who have been clinically diagnosed with generalized moderate to severe chronic periodontitis, otherwise systemically healthy, based on American Academy of Periodontology 1999 classification found to have clinical attachment loss more than or equal to 3mm in 30% of the sites and probing pocket depth more than or equal to 5mm with at least 6 teeth.

Exclusion criteria

Exclusion criteria: Patients with history of any systemic disease Pregnancy or lactation Current or former smokers Patients with history of periodontal therapy in the last 6 months Patients with history of antibiotic intake in the last 3 months Patients with history of anti-inflammatory drug therapy in the last 3 months Patients consuming any other medications Patients with any intra oral lesions

Design outcomes

Primary

MeasureTime frame
Salivary and serum fetuin-A levels. Probing pocket depth clinical attachment level bleeding on probingTimepoint: Baseline and 3 months

Secondary

MeasureTime frame
Gingival index plaque indexTimepoint: 3 months

Countries

India

Contacts

Public ContactDr Sanjita Nair

Rajiv Gandhi University of Health Sciences

nisharejath@gmail.com8105490909

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026