Autologous platelet rich plasma in dry eye disease

Evaluate the efficacy of topical autologous platelet rich plasma in treatment of moderate- severe dry eye.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/03/031887

Enrollment

Registered

2021-03-10

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H048- Other disorders of lacrimal system

Interventions

Intervention1: Autologous-Platelet Rich Plasma: Autologous-Platelet Rich Plasma eye drop (20%) in dry eye disease Control Intervention1: ARTIFICIAL TEAR: ARTIFICIAL TEAR (0.5 % carboxy methyl cellulos

Eligibility

Inclusion criteria

Inclusion criteria: 1.Schirmerâ??s 2.TBUT 3.Age range: 18 years - 90 years. 4.Able to acknowledge and give informed written consent. 5.Able to co-operate with the investigational plan and obey all mandatory follow-up visits.

Exclusion criteria

Exclusion criteria: 1.Patients who are unwilling or unable to give consent, refuse to accept randomization, or to return for scheduled visits. 2.Involved in other clinical trial. 3.Uncooperative patients. 4.Patients under 18 or more than 90 years age. 5.Pregnant females or expecting to become pregnant during the study. 6.AIDS or other systemic immune deficient conditions or are under systemic immunosuppressants. 7.Contact lens wear 8.Active ocular infection 9.Unable to close eyes or uncontrolled blinking

Design outcomes

Primary

Measure	Time frame
Improvement in following parameters after using a-PRP eye drop in dry eye disease OSDI score Schirmer test score (mm) TBUT score (sec) CFS score TMH (mm) Lissamine Green staining score Rose Bengal staining scoreTimepoint: 3 months	—

Secondary

Measure	Time frame
To evaluate the duration and associated complications of using a-PRP eye drop in dry eye diseaseTimepoint: 3 months	—

Countries

India

Contacts

Public ContactRitika Agrawal

MGM Medical College

drpreeti.eye@rediffmail.com9826034458

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026