Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intravenous injection of fentanyl as a premedication: Evaluation of efficacy of Intravenous injection of fentanyl 2 mcg/kg or 3 mcg/kg to prevent pressure response of laryngoscopy and i
Sponsors
Government of Gujarat
Eligibility
Inclusion criteria
Inclusion criteria: Informed written consent. Patients posted for elective surgery under general Anesthesia requiring endotracheal intubation. ASA physical status || Well controlled primary idiopathic hypertension(blood pressure less then or equal to 140/90) with maximum three anti hypertensive medications excluding beta blockers. No end organ involvement due to hypertension. BMI less then or equal to 25. Modified Mallampati classification | and ||.
Exclusion criteria
Exclusion criteria: Patient refusing for consent. Patients with diabetes, COPD, renal disease, cardiac diseases like IHD, valvular heart disease, AV conduction block, aortic stenosis, left ventricular failure etc. Patient on drugs(sedatives,opioids,anti-psychotic drugs and beta blockers). Anticipated difficult intubation. BMI more then or equal to 25. Intubation attempt lasting longer than 15 seconds. Patient on more than 3 anti hypertensive medications. Defaulter of taking anti hypertensive medications as per schedule.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Variation in heart rate, systolic blood pressure, diastolic blood pressure, ST-T changes, cardiac rhythm changesTimepoint: From injection of intravenous fentanyl to 20 minutes after endotracheal intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| To asses sedative effect of fentanyl and to observe any complicationsTimepoint: From injection of intravenous fentanyl to 60 minutes after endotracheal extubation | — |
Countries
India
Contacts
Public ContactDr Dipshikha tripathi
B.J.medical college
Outcome results
None listed