Health Condition 1: D67- Hereditary factor IX deficiency Health Condition 2: D66- Hereditary factor VIII deficiency
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients diagnosed with Haemophilia A or B Patients with haemophilic arthropathy with at least one target joint involvement (elbow or knee) Patients above 18 years of age
Exclusion criteria
Exclusion criteria: Patients diagnosed with any other congenital bleeding disorders i.e. Von Willebrand disease. Patients receiving regular physiotherapy for elbow or knee joint(s) prior to commencement of study. Patients with any fixed deformity of knee or elbow joint(s). Patients who have undergone elbow/knee synovio arthesis within last 6 months. Patients who do not give informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WFH Gilbert ScoreTimepoint: Baseline Day 0 Midterm Day 10 Post Intervention Day 21 Follow up at 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Range of Motion for Knee and Elbow Joint (using Goniometer)Timepoint: Baseline Day 0 Midterm Day 10 Post Intervention Day 21 Follow up at 3 months;Manual Muscle Testing using hand held DynamometerTimepoint: Baseline Day 0 Midterm Day 10 Post Intervention Day 21 Follow up at 3 months;Haemophilia Joint Health Status (HJHS)Timepoint: Baseline Day 0 Midterm Day 10 Post Intervention Day 21 Follow up at 3 months;Functional Independence Scoring for Haemophilia (FISH)Timepoint: Baseline Day 0 Midterm Day 10 Post Intervention Day 21 Follow up at 3 months;EQ-5D-5LTimepoint: Baseline Day 0 Midterm Day 10 Post Intervention Day 21 Follow up at 3 months | — |
Countries
India
Contacts
Christian Medical College and Hospital, Ludhiana