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presence of erbB receptors and estrogen receptors on the inner lining of the uterus during tumor of ovary

Expression of erbB receptor family and estrogen receptors(ER) in endometrium and ectopic lesion during ovarian endometriosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/03/031825
Enrollment
140
Registered
2021-03-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N801- Endometriosis of ovary

Interventions

None listed

Sponsors

All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients enrolled for a surgical intervention for endometriosis or evaluation at the Infertility diagnosed by stages III-IV ovarian

Exclusion criteria

Exclusion criteria: a)Presence of any other endocrinological disorder or uterine cancer b)Fibroids c) Adenomyosis d) Abnormal uterine bleeding e)Pelvic tuberculosis f)History of hormonal treatment

Design outcomes

Primary

MeasureTime frame
To assess the localization and expression of EGFR, erbB-2, erbB-3, erbB-4 and estrogen receptors (ERα and ERβ) in paired samples of OE group and eutopic endometrium of control groupTimepoint: 2 year—

Secondary

MeasureTime frame
1.To correlate, the expression pattern of estrogen receptors in these tissues with the findings of the erbB-expression. 2.To compare the expression pattern of estrogen receptors and erbB-expression between fertile/infertile and proliferative/secretory subgroups to investigate the association of these expression patterns with fertility and menstrual phase. 3.To investigate the possible role of the erbB receptor family in the development and progression of ovarian endometriosis Timepoint: 2 year—

Countries

India

Contacts

Public ContactDr Deepali Garg

All India Institute of Medical Sciences

drdeepaligarg@gmail.com9818706660

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026