FindTrial
Sign In

Effect of melatonin on incidence of post-operative delirium.

To study the effect of premedication with oral melatonin on incidence of post-operative delirium in patients undergoing elective surgery under general anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/03/031804
Enrollment
162
Registered
2021-03-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: F418- Other specified anxiety disorders

Interventions

Intervention1: Melatonin premedication in patients undergoing elective surgery under general anaesthesia: Premedication with oral melatonin in addition to routine premedication (alprazolam) versus rou

Sponsors

Pgimer chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Asa1 and 2

Exclusion criteria

Exclusion criteria: Asa 3 and 4, age >80yr <40 yrs, patients having allergy to study drugs, patients with mental illness, patients on steroids and antipsychotic and anticholinergic drugs, patients unable to read or write basic alphabets, patients with uncontrolled hypertension and diabetes, thyroid disorder patients

Design outcomes

Primary

MeasureTime frame
To compare effects of melatonin versus no melatonin on incidence of post-operative deliriumTimepoint: Preoperatively upto postoperatively 6hrs, 24hrs, 48hrs,and 72 hrs postoperatively—

Secondary

MeasureTime frame
To evaluate influence of melatonin on anxiety score, sedation, cognition and side effectsTimepoint: Preoperatively upto postoperatively 6hrs, 24hrs, 48hrs,and 72 hrs postoperatively—

Countries

India

Contacts

Public ContactTanuja Thakur

Pgimer chandigarh

drvsaini@gmail.com7087008119

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026