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Study of safety and duration of action of single dose (7.5 units) of botulinum toxin injection in patients with functional epiphora and proximal lacrimal drainage block

Study of safety and outcome of botulinum toxin injection in patients with functional epiphora and proximal lacrimal drainage block

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/03/031793
Enrollment
31
Registered
2021-03-08
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H042- Epiphora

Interventions

Intervention1: Inj Botulinum Toxin: Injection Botulinum toxin 7.5 units given in palpebral lobe of lacrimal gland for treatment of epiphora Intervention2: Inj Botulinum Toxin: Injection Botulinum toxi

Sponsors

Dept of Ophthalmology Command Hospital Kolkata
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Punctal stenosis, Proximal canalicular block, Lacrimal pump failure, Failed DCR

Exclusion criteria

Exclusion criteria: Those who do not give consent, Ocular infections, Dry eye disease, Any cause of reflex lacrimation, Ocular allergic disorders

Design outcomes

Primary

MeasureTime frame
Outcome of botulinum toxin and duration of action in treatment of functional epiphora and proximal canalicular blockTimepoint: Day 01, 15 days, 1 month, 02 months, 03 months, 04 months 05 months, 06 months—

Secondary

MeasureTime frame
To assess the side effects associated with botulinum toxin injected into the lacrimal glandTimepoint: Day 01, 15 days, 1 month, 02 months, 03 months, 04 months, 05 months, 06 months—

Countries

India

Contacts

Public ContactDr Nava Raj Rizal

Command Hospital Eastern Command

raobv911@gmail.com7875930365

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026