USE OF BILASTINE VS LEVOCETRIZINE FOR ITCHY SKIN RASH

COMPARISON OF THE EFFICACY OF BILASTINE VERSUS LEVOCETIRIZINE FOR THE TREATMENT OF CHRONIC SPONTANEOUS URTICARIA

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/03/031785

Enrollment

Registered

2021-03-08

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L501- Idiopathic urticaria

Interventions

Intervention1: DAILY ADMINISTRATION OF ANTIHISTAMINES: DAILY ADMINISTRATION OF BILASTINE AND LEVOCETIRIZINE FOR 2 MONTH Control Intervention1: DAILY SINGLE DOSE ANTIHISTAMINE: BILASTINE 20MG FOR ONE G

Eligibility

Inclusion criteria

Inclusion criteria: All patients of age >18 years presenting to Dermatology department with CSU who are not on any drug for urticaria for the past one week.

Exclusion criteria

Exclusion criteria: 1. Patients above 65 years. 2. Pregnant and lactating women. 3. Other pruritic disorders like eczema, contact dermatitis, and atopic dermatitis. 4. Patient on drug which cause sedation like antipsychotic drugs

Design outcomes

Primary

Measure	Time frame
the efficacy of oral Bilastine 20 mg and Levocetirizine 10 mg in patients with Chronic Spontaneous Urticaria will be assessed by using Urticaria Activity Score (UAS), Urticaria Severity Score (USS), Urticaria control test (UCT), Chronic Urticaria Quality Of Life (CU-Q2OL).Timepoint: mean difference in efficacy of oral Bilastine 20 mg and Levocetirizine 10 mg in patients with Chronic Spontaneous Urticaria will be assessed by using Urticaria Activity Score (UAS), Urticaria Severity Score (USS), Urticaria control test (UCT), Chronic Urticaria Quality Of Life (CU-Q2OL) in day 28 an 56 days	—

Measure

Time frame

the efficacy of oral Bilastine 20 mg and Levocetirizine 10 mg in patients with Chronic Spontaneous Urticaria will be assessed by using Urticaria Activity Score (UAS), Urticaria Severity Score (USS), Urticaria control test (UCT), Chronic Urticaria Quality Of Life (CU-Q2OL).Timepoint: mean difference in efficacy of oral Bilastine 20 mg and Levocetirizine 10 mg in patients with Chronic Spontaneous Urticaria will be assessed by using Urticaria Activity Score (UAS), Urticaria Severity Score (USS), Urticaria control test (UCT), Chronic Urticaria Quality Of Life (CU-Q2OL) in day 28 an 56 days

—

Secondary

Measure	Time frame
To assess the degree of somnolence produced by both drugs using Epworth Sleepiness Scale (ESS).Timepoint: Mean difference in Somnolence between two groups at day 28 and 56 days.	—

Countries

India

Contacts

Public ContactDr Sheela Kuruvila

Pondicherry Institute of Medical Sciences

kuruvilasheela@gmail.com9047038527

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026