Health Condition 1: C509- Malignant neoplasm of breast of unspecified site Health Condition 2: C509- Malignant neoplasm of breast of unspecified site
Conditions
Interventions
Intervention1: Dexamethasone: Adding 8 mg dexamethasone as an adjuvant to 0.2% ropivacaine vs plain 0.2% ropivacaine in patients undergoing modified radical mastectomy
Control Intervention1: Plain rop
Sponsors
Dr Porika Prashanth Nayak
Eligibility
Inclusion criteria
Inclusion criteria: 1)Female patients aged 18 years and above 2)Posted for unilateral elective MRM 3)Belonging to American society of Anaesthesiologists (ASA) grade I, II, III
Exclusion criteria
Exclusion criteria: 1)Patients refusal. 2)Contraindications to regional anesthesia (RA) (bleeding diathesis, infection at the site of block and peripheral neuropathy). 3)Allergy to study drugs. 4)BMI � 35 kg/m2 or body weight � less than 40kg. 5)Chest wall deformity. 6)Patients who have undergone prior breast surgery. 7)Psychiatric patients. 8)Pregnant and lactating patients. 9)Any untoward major intra-operative complication (if any). (severe hypotension, bradycardia any injury to the nerve related to the block)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total opioid consumption till 12 hours post-operatively.Timepoint: 0 hours(when patient arrived at post-operative care unit), 2 hours, 4 hours, 6 hours and 12 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Difference in pain scores post-operatively in first 12 hours using numeric rating scale (NRS). 2)Post-operative sedation scores. 3)Incidence and severity of post-operative nausea and vomiting (PONV). 4)Other adverse events (if any). Timepoint: 0 hours, 2 hours, 4 hours, 6 hours, 12 hours post-operatively. | — |
Countries
India
Contacts
Public ContactDr Porika Prashanth Nayak
All India Institute Of Medical Sciences, RAIPUR
Outcome results
None listed