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Fasting and Carbohydrate fluid responsiveness on preload during passive leg raise test in patients undergoing thoraco- abdominal surgeries

Comparison of pre-operative oral carbohydrate fluid vs overnight fasting on preload responsiveness during passive leg raise test in patients undergoing elective thoraco- abdominal surgeries ââ?¬â?? an exploratory randomized cross-over trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/03/031776
Enrollment
52
Registered
2021-03-08
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J851- Abscess of lung with pneumonia Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: patient is given carbohydrate fluid one night before surgery. In night echo is done and VTI noted in semi recumbent position and after PLR. Then carbohydrate fluid is given in night.: I

Sponsors

AIIMS Rishikesh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Elective thoracic and upper abdomen surgery 2. Age 18-60 years 3. Both gender male and female 4. ASA I ââ?¬â?? III 5. LVEF > 45% 6. Patients admitted at least 2 days before surgery 7. Patients posted as 1st case elective surgery

Exclusion criteria

Exclusion criteria: 1 Emergency surgery 2 Age less than 18years or more than 60 years 3 ASA IV and above 4 Patient in need of bowel preparation. 5 Patient with cardiac arrhythmia or valvular pathology 6 Poor echo window 7 2nd case planned for surgery. 8 BMI >30 9 Patients with renal insufficiency (S. creatinine �2.0mg/dl) 10 Patients on diuretic medication. 11 Uncontrolled DM 12 Patients requiring intravenous fluid before surgery

Design outcomes

Primary

MeasureTime frame
To compare change in proportion of responders by measuring change in percentage velocity time integral over left ventricle outflow tract to passive leg raise test between patients with pre-operative oral carbohydrate solution and with conventional overnight fastingTimepoint: T1- day 1 night patient in semi recumbent position T2- day 1 night patient after PLR T3- day 2 morning after intervention fasting/carbohydrate fluid patient in semi recumbent position T4- day 2 morning patient after PLR T5- day 2 night patient in semi recumbent T6- day 2 night patient after PLR T7- day 3 morning patient after intervention cross over other than previos intervention, in semi recumbent position T8- patient after PLR

Secondary

MeasureTime frame
A) To compare the proportion of patients having significant change in grading of diastolic dysfunction using parameters of left ventricle diastolic dysfunction as Mitral valve inflow E/A ratio, Mitral valve annulus e� velocity, E/e� ratio and peak Tricuspid regurgitation velocity after conventional overnight fasting and carbohydrate loading during surgery Timepoint: As the same point as primary outcome, diastolic dysfunction is noted as secondry outcome. there is mo follow up time point in the study

Countries

India

Contacts

Public ContactDr Vikas Yadav

AIIMS Rishikesh

ajaymishra0701@gmail.com9340482058

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026