Comparison of treatment of bony defect around teeth with the help of bone graft alone versus bone graft with blood products.

Regenerative potential of titanium platelet rich fibrin with and without demineralized freeze dried bone allograft in the treatment of intrabony defects-: a comparative clinico-radiographic study.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/03/031751

Enrollment

Registered

2021-03-05

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: open flap debridement with T-PRF and DFDBA.: vertical intrabony alveolar defects will be treated with open flap debridement and filled with Demineralized freeze dried bone allograft (DF

Eligibility

Inclusion criteria

Inclusion criteria: Patients with chronic periodontitis exhibiting radiographic evidence of intrabony defects

Exclusion criteria

Exclusion criteria: Patients with contraindication to periodontal surgery & local anesthesia. Any systemic disease affecting the bone density and outcome of periodontal therapy. Smokers, alcoholics, and patients with other adverse habits. Pregnant, nursing and menopausal women. Any known allergy/ hypersensitivity to any product used in this study. Patients on long-term systemic therapy (antibiotics, anti-inflammatory bisphosphonates, hormonal replacement therapy and any other), taking any drug known to have periodontal implications that may interfere with wound healing. Patients taking any anti-platelet and anticoagulant medication. Patients who have undergone periodontal treatment within a period of past 1 year.

Design outcomes

Primary

Measure	Time frame
radiographic bone fillTimepoint: baseline,6 months	—

Secondary

Measure	Time frame
Clinical attachment levelTimepoint: baseline, 3 months,6 months;probing pocket depthTimepoint: baseline, 3 months,6 months	—

Countries

India

Contacts

Public ContactDeepak Kochar

Mahrishi markandeshwar college of dental sciences

sksperio@gmail.com8199980802

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026