Comparison of two drugs in spinal anesthesia for pain relief in post operative period

Comparison of Post Operative Analgesia between Intrathecal Nalbuphine VS Fentanyl in Spinal Anaesthesia - A Double blinded Randomised Controlled Study

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/03/031729

Enrollment

166

Registered

2021-03-05

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Postoperative pain: Injection diclofenac 75mg iv stat Control Intervention1: Analgesic: Injection diclofenac Control Intervention2: Nalbuphine: 0.5% bupivacaine 2.5ml and Nalbuphine 1mg

Eligibility

Inclusion criteria

Inclusion criteria: 1Patients belonging to ASA I & II 2Aged between 18 & 65 years 3 Patient undergoing elective infra umbilical surgeries

Exclusion criteria

Exclusion criteria: 1Patients with raised intracranial pressure or any intracranial pathology 2 Hypovolemia, Bradycardia 3 Patients on anticoagulants 4 Localised infection 5 Pregnant women 6 Allergy to local anaesthetics.

Design outcomes

Primary

Measure	Time frame
to compare the duration of analgesia of nalbuphine and fentanyl in postoperative period in addition to bupivacaine in spinal anesthesia by using VAS scoreTimepoint: 24 hours	—

Secondary

Measure	Time frame
1) to compare the onset and duration of sensory and motor blockade 2)to compare the hemodynamic parametersTimepoint: 24hours	—

Countries

India

Contacts

Public ContactDr hariharasudhan

Pondicherry institute of medical sciences

hsknight071@gmail.com8861085422

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026