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prevention of intrautrine adhesion using PRP folllowing surgical abortion

role of intrauterine instillation of autologous platelet rich plasma in the prevention of formation of intruterine synechiae following surgical abortion.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/03/031712
Enrollment
50
Registered
2021-03-04
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O048- (Induced) termination of pregnancywith other and unspecified complications

Interventions

Intervention1: DILATATION AND EVACUATION WITH AUTOLOGOUS PLATELET RICH PLASMA: following dilatation and evacuation for termination of pregnancy, 1-1.5 ml of autologous PLATELET RICH PLASMA will be ins

Sponsors

AIIMS Patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: PATIENTS WITH 1) Period of gestation 2) Autologous platelet count > 105/ uL 3) Consent given by the patient 4) Patient undergoing surgical abortion

Exclusion criteria

Exclusion criteria: 1) Age 45years 2) Bleeding diathesis 3) Platelet count 4) Concomitant active genitourinary infection 5) Patient taking anticoagulants 6) Clinical evidence of any malignancy 7) Patient’s refusal 8) Hemoglobin 9) Use of NSAIDS within 10days prior to instillation. 10) Patients developing post abortion infection

Design outcomes

Primary

MeasureTime frame
To estimate the degree of intrauterine synechiae after surgical abortion following intrauterine infusion of autologous platelet rich plasma using AFS scoring on hysteroscopy. Timepoint: 8 WEEKS POST PROCEDURE

Secondary

MeasureTime frame
1) To study the relation between the number of pregnancy loss & severity of intrauterine adhesions & to correlate the AFS scoring on hysteroscopy with period of gestation at the time of surgical abortion. 2) To evaluate risk factors for the development of intrauterine synechiae. Timepoint: 8 WEEKS

Countries

India

Contacts

Public ContactAkanksha Singh

AIIMS PATNA

sangam.jha78@gmail.com9827388001

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026