Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: This study will be conducted on patients, of either sex, 18 â?? 85 years old, American Society of Anaesthesiologists (ASA) physical status I or II, scheduled for elective total knee replacement surgery under spinal anaesthesia.
Exclusion criteria
Exclusion criteria: 1. Contraindications to blocks (like patients with coagulopathy or taking anticoagulants and local infection at the site of needle insertion). 2. Patients with history of hypersensitivity or allergy to drugs used in the study. 3. Patients suffering from cardiac, renal, hepatic and respiratory insufficiency. 4. Preexisting neurological deficits.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain assessed by Numerical Rating Scale (NRS)Timepoint: at 2 hrs, 4 hrs, 8 hrs, 12 hrs, 24 hrs, and 48 hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of analgesia (Time to first rescue analgesia, sensory level regression recorded)Timepoint: at 2 hrs, 4 hrs, 8 hrs, 12 hrs, 24 hrs, and 48 hrs;Total morphine consumptionTimepoint: at 2 hrs, 4 hrs, 8 hrs, 12 hrs, 24 hrs, and 48 hrs | — |
Countries
India
Contacts
VMMC and Safdarjung Hospital, New Delhi