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Comparison of commercially available bone graft alone and along with blood product in the treatment bony defect around teeth.

Regenerative potential of advanced platelet rich fibrin and bioactive glass in the treatment of intrabony defects: a comparative clinico radiographic study�

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/02/031587
Enrollment
45
Registered
2021-02-26
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: open flap debridement and filled Bioactive glass (Perioglas�®) and Advanced Platelet Rich Fibrin: vertical intrabony alveolar defects will be treated with open flap debridement and fi

Sponsors

Mahrishi markandeshwar college of dental sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with chronic periodontitis exhibiting intrabony defects.

Exclusion criteria

Exclusion criteria: Patients with contraindication to periodontal surgery & local anesthesia. Any systemic disease affecting the bone density and outcome of periodontal therapy. Smokers, alcoholics, and patients with other adverse habits. Pregnant, nursing and menopausal women. Any known allergy/ hypersensitivity to any product used in this study. Patients on long-term systemic therapy (antibiotics, anti-inflammatory bisphosphonates, hormonal replacement therapy and any other), taking any drug known to have periodontal implications that may interfere with wound healing. Patients taking any anti-platelet and anticoagulant medication. Patients who have undergone periodontal treatment within a period of past 1 year.

Design outcomes

Primary

MeasureTime frame
radiographic bone fillTimepoint: baseline,6 months

Secondary

MeasureTime frame
probing pocket depthTimepoint: baseline,6 months;Relative attachment levelTimepoint: baseline,6 months

Countries

India

Contacts

Public ContactDeepak Kochar

Mahrishi markandeshwar college of dental sciences

sksperio@gmail.com8199980802

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026