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Two different Oxytocin dosage given to reduce bleeding for cesarean operation . Note: oxytocin is commonly used drug, given to make the uterus contract after baby delivery

â??A comparative study between oxytocin bolus with infusion versus oxytocin infusion in minimizing uterine bleeding following Caesarean section: A randomized control trialâ??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/02/031583
Enrollment
120
Registered
2021-02-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O94- Sequelae of complication of pregnancy, childbirth, and the puerperium

Interventions

Intervention1: iv oxytocin bolus with infusion: i.v slow bolus of oxytocin 3 IU (3 IU diluted to 3ml with sterile water) over 1 minute and 15 IU oxytocin in 500 mL of 0.9% saline solution infused at 1

Sponsors

AJ Institute Of Medical Sciences And Research Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: singleton/Twin pregnancies ( >34 weeks) posted for elective caesarean section

Exclusion criteria

Exclusion criteria: Women with placenta previa, thrombocytopenia, coagulopathies, previous major obstetric haemorrhage ( >1000 mL), fibroids, or women who are receiving anticoagulant treatment

Design outcomes

Primary

MeasureTime frame
1. To compare the uterine tonicity between the group receiving oxytocin bolus with infusion and the group receiving oxytocin infusion only. 2. To determine the need for additional uterotonic agents between the group receiving oxytocin bolus with infusion and the group with oxytocin infusion only. Timepoint: 1. intra-operative; after the extraction of foetus, till the completion of surgery. 2. post-operative period, up to 24 hours.

Secondary

MeasureTime frame
1. To assess the amount of blood loss in women undergoing cesarean sections between the two groups. 2. To assess the need for additional blood transfusion perioperatively between the two groups. Timepoint: Intraoperative and 24hrs Postoperative period

Countries

India

Contacts

Public ContactHarish Karanth

A.J Institute of Medical Sciences and Research Centre

harishkrnth@gmail.com09900910374

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026