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TO STUDY THE EFFECT OF LASER THERAPY ON PAINFELT DURING ORTHODONTIC ALIGNMENT AND ITS RELATION WITH PG-E2 LEVELS.

THE EFFECT OF LOW LEVEL LASER THERAPY ON PAIN PERCEPTION AND ITS CORRELATION WITH PGE2 LEVELS DURING ORTHODONTIC ALIGNMENT - A SPLIT MOUTH STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/02/031531
Enrollment
20
Registered
2021-02-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K088- Other specified disorders of teethand supporting structures

Interventions

Intervention1: Low level laser therapy: the laser unit is a 940nm aluminium gallium arsenide diode laser (iLase
Biolase, Irvine, CA, USA). it will be set on continuous mode with power output of 100mW with 200 micromeer fibre tip. the mucosa will be irradiated on 5 points buccally and palatally per tooth for 3 s

Sponsors

JASLEEN KAUR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Fixed orthodontic treatment with Angle Class II division 1 good general health, healthy periodontal tissues, no radiographic evidence of periodontal bone loss

Exclusion criteria

Exclusion criteria: subjects who require extractions for initial alignment and leveling Subjects with systemic diseases Subjects on periodic prescription drugs affecting pain perception. subjects with parafunctional habits

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the pain intensity using visual analogue scale after the placement of orthodontic archwire at different time intervals on the experimental side and the placebo side.Timepoint: 1 hour, 24 hours, 7 days after the placement of the archwire

Secondary

MeasureTime frame
to evaluate and compare the PGE2 levels in GCF at different time intervals on experimental side and placebo side to check any correlation between the PGE2 level and visual Analogue score in patients who may or may not be subjected to low level laser therapyTimepoint: before placement of archwire, after 24 hours and 7 days of orthodontic archwire placement.

Countries

India

Contacts

Public ContactJASLEEN KAUR

ITS CDSR MURAD NAGAR

piushkumardf@its.edu.in9811307935

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026