TO EVALUATE HEALING OF PERIODONTAL TISSUES USING SIMVASTATIN 1.2% GEL AS A LOCAL DRUG DELIVERY ALONG WITH SCALING AND ROOT PLANING IN CHRONIC PERIODONTITIS PATIENTS -A CLINICAL STUDY

EVALUATION OF HEALING OF PERIODONTAL TISSUES WITH AND WITHOUT SIMVASTATIN 1.2% GEL AS A LOCAL DRUG DELIVERY IN ADJUNCT TO SCALING AND ROOT PLANING IN CHRONIC PERIODONTITIS PATIENTS -A CLINICAL STUDY

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/02/031513

Enrollment

Registered

2021-02-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: SIMVASTATIN 1.2 % : 10 microlitre simvastatin in gel form at baseline to assess clinical parameters like PROBING POCKET DEPTH, CLINICAL ATTACHMENT GAIN, PERCENTAGE OF BONE FILL at basel

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients willing to participate in the study. 2.Patients aged between 25-50 years. 3.Systemically healthy patients with chronic moderate periodontitis. 4.Patients with localized probing pocket depth of >=4 5.Patients with clinical attachment loss of >= 4 mm. 6. Patients with vertical bone loss of 7.Patients not being subjected to/willingfor periodontal surgery for the same as above mentioned criterias

Exclusion criteria

Exclusion criteria: .Patients who are unable to provide information or to co-operate with the dental examination. 2.Patients who have undergone any periodontal, surgical or non-surgical therapy for past 6 months. 3.Patients who have received any chemotherapeutic mouth rinse or oral irrigation during the past 6 months. 4.Patients who have received antibiotics and anti-inflammatory drugs in the past 4-6 weeks and during the study. 5.Patients with a history of underlying systemic diseases and condition. 6.Patients diagnosed with trauma from occlusion 7.Patients with a habit of smoking, tobacco chewing, and alcohol consumption. 8.Pregnant and lactating women and those using hormonal contraceptives

Design outcomes

Primary

Measure	Time frame
Probing pocket depth,clinical attachment level gainTimepoint: 3 months,6 months,9 months	—

Secondary

Measure	Time frame
percentage of bone fillTimepoint: 6 months,9 months	—

Countries

India

Contacts

Public ContactDR DEVISHREE CP

AJ INSTITUTE OF DENTAL SCIENCES

manjusreekadam@gmail.com9448158952

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026