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Comparative study between volume controlled and pressure controlled ventilation in one lung ventilation during decortication(surgical procedure to remove fibrous layer around lung tissue) for empyema thoracis

Volume versus Pressure controlled ventilation during one lung ventilation in decortication for empyema thoracis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/02/031499
Enrollment
60
Registered
2021-02-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J683- Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapors

Interventions

Intervention1: Pressure controlled ventilation: Arterial blood gas analysis will be performed pre-operatively,intra-operatively after 1 hour of one lung ventilation and then finally after extubation.

Sponsors

King George medical university
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient posted for elective decortication surgery forempyema thoracis requiring lung isolation technique of ASA grade 2 and 3 between 20-50 years

Exclusion criteria

Exclusion criteria: Major organ dysfunction except lung disease,hemodynamic instability,increased intracranial pressure Age >50 years Difficult airway H/o chest wall deformity or thoracic surgery that could interfere with pulmonary resection Non pulmonary co morbities that could cause severe functional limitation(morbid obesity) or could limit survival(cancer) Pulmonary hypertension at rest

Design outcomes

Primary

MeasureTime frame
During surgery, haemodynamic monitoring (SBP,DBP, MAP, HR,ETCO2) is done continuously and noted at 0,5,15,30 AND 45 minutes intra operatively.Timepoint: During surgery, haemodynamic monitoring (SBP,DBP, MAP, HR,ETCO2) is done continuously and noted at 0,5,15,30 AND 45 minutes intra operatively.

Secondary

MeasureTime frame
Plateau and peak pressures are recorded at all these stages including the basic parameters of the body like BP,HR,etco2 and arterial oxygen saturation independently during volume controlled and pressure controlled ventilation. Intra-operatively multimodal methods of analgesia will be used including inj.fentanyl,inj.PCM (1 gm) and intercostal block on the thoracotomy sideTimepoint: 24hrs

Countries

India

Contacts

Public ContactDinesh Singh

King George medical university

dineshkgmu@yahoo.com7905492858

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026