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Evaluation of a biomarker levels(peptidyl arginine dieminase 2) in patients with severe gum disease before and after professional cleaning of tooth and root surface and after gum surgery.

â??COMPARATIVE EVALUATION OF PEPTIDYLARGININE DEIMINASE 2 LEVELS IN GINGIVAL CREVICULAR FLUID OF PATIENTS WITH CHRONIC PERIODONTITIS BEFORE AND AFTER SCALING AND ROOT PLANING AND FLAP SURGERY- A CLINICO BIOCHEMICAL STUDY â??â??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/02/031474
Enrollment
20
Registered
2021-02-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Scaling and rootplaning: scaling and rootplaning is done in the first appointment Intervention2: flap surgery: flap surgery is done two weeks after scaling and rootplaning Control Inter

Sponsors

Abhiraami
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects with a minimum complement of 20 teeth. Subjects with chronic periodontitis indicated for flap surgery.

Exclusion criteria

Exclusion criteria: Subjects with any systemic disease. Subjects who have undergone any periodontal treatment in the last 6 months. Subjects who have received antibiotics/anti-inflammatory drugs/steroids immunosuppressive chemotherapy within the last 6 months.

Design outcomes

Primary

MeasureTime frame
reduction of clinical parameters and reduction of PEPTIDYLARGININE DEIMINASE 2Timepoint: reduction of clinical parameters and reduction of PEPTIDYLARGININE DEIMINASE 2 from baseline to 2 weeks

Secondary

MeasureTime frame
gradual reduction of clinical parameters and gradual reduction of PEPTIDYLARGININE DEIMINASE 2Timepoint: gradual reduction of clinical parameters and gradual reduction of PEPTIDYLARGININE DEIMINASE 2 from baseline to two months

Countries

India

Contacts

Public ContactAmit Walvekar

coorg institute of dental sciences

abhiraami.shaji@gmail.com09483429573

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026