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Comparing a salivary and blood agent before and after cleaning of teeth in patients with disease of gums and underlying bone with and without diabetes

Comparison of salivary and serum sTWEAK levels before and after scaling and root planing in patients with periodontitis with and without type 2 diabetes mellitus - SSTD

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/02/031469
Enrollment
45
Registered
2021-02-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Non Surgical Periodontal Therapy: Scaling and root planing Control Intervention1: NIL: NIL

Sponsors

DR ARUNAV GOGOI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Presence of minimum of 16 natural teeth, systemically healthy patients (Group 1) with no signs of gingival inflammation defined by gingival index score less than 0.5 and without periodontal clinical attachment loss and bone loss, systemically healthy patients with periodontitis ( group 2) clinically diagnosed based on 2017 World Workshop on the Classification of Periodontal and Peri-implant diseases and conditions having clinical attachment loss greater than equal to 3mm in 30 % of the sites and probing pocket depth greater than equal to 4mm with at least two teeth, Periodontitis patient with type 2 diabetes mellitus, Patients with type 2 diabetes mellitus diagnosed at-least one year prior to the study using diagnostic criteria of the American Diabetes Association.

Exclusion criteria

Exclusion criteria: Patients with any other systemic disease accompanying type 2 diabetes mellitus, patients with type 1 diabetes mellitus, Pregnancy or lactation, Current or former smokers, Patients with history of antibiotic intake within past 3 months, patients with history of anti-inflammatory drug therapy within 3 months, patients taking any other medication excluding medication for diabetes mellitus, patients with any intra oral lesions

Design outcomes

Primary

MeasureTime frame
Probing Pocket Depth, Clinical Attachment Level.Timepoint: 3 months

Secondary

MeasureTime frame
Plaque Index, Gingival index, Percentage of Bleeding sitesTimepoint: 3 months

Countries

India

Contacts

Public ContactDr Arunav Gogoi

Rajiv Gandhi University of Health Sciences, Karnataka

sanjeelaguru@gmail.com7259665551

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026