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Effect of long duration fasting and short duration fasting on intravascular volume status and stress hormone levels.

A comparison between patients observing long duration and short duration fasting before surgery, with respect to intravascular volume status and stress hormone levels: A prospective single blinded observational study.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/02/031456
Enrollment
70
Registered
2021-02-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis Health Condition 2: K80- Cholelithiasis

Interventions

Intervention1: NIL: NIL

Sponsors

ICMR THESIS GRANT
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria for study participants â?? 1) Age more than 18years and less than 60 years 2) ASA I/II. 3) Patients undergoing laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: Exclusion criteria for study participants â?? 1) BMI more than 30. 2) Diabetic patients. 3) Hypertensive patients. 4) Patients receiving exogenous thyroid supplements or anti-thyroid medications. 5) Pregnant females. 6) ASA grade III and IV. 7) Major blood loss during surgery. 8) Missing data on study variables. 9) Patients refusing informed consent. 10) Patients receiving medications known to interfere with hormonal response to stress.

Design outcomes

Primary

MeasureTime frame
To measure and compare the status of intravascular volume by measurement of inferior vena cava collapsibility index (IVCCI) following conventional midnight fasting and shortened fasting protocol in patients undergoing laparoscopic cholecystectomy.Timepoint: Before surgery, in the preoperative area all the patients shall undergo ultrasonography assisted measurement of Inferior vena cava collapsibility index (IVCCI).—

Secondary

MeasureTime frame
To measure and compare the levels of stress hormones (fT4, serum cortisol, C-peptide, C-reactive protein) in response to moderate stress surgeries following conventional midnight fasting and fasting recommendation of ERAS protocol in patients undergoing laparoscopic cholecystectomy.Timepoint: Venous blood samples would be drawn for the measurement of biochemical parameter and would be sent to Biochemistry department at predefined time points i.e, at 8pm on the day before surgery (one hour before the dinner), on the day of the surgery at 7am (2hours before surgery), 1 hour after the tracheal extubation and 24 hours after the surgery. All the samples shall be drawn from the anticubital vein after application of tourniquet.—

Countries

India

Contacts

Public ContactAishwary Shivhare

AIIMS Bhopal

anuj.jain.mln@gmail.com9755702644

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 13, 2026